Table 1 Tissue weight (g) of 23 weeks old mice on LFD or HFD.

From: Overexpressing the novel autocrine/endocrine adipokine WISP2 induces hyperplasia of the heart, white and brown adipose tissues and prevents insulin resistance

 

LFD wt

LFD Tg

P-value

HFD wt

HFD Tg

P-value

Heart

0.126 ± 0.003

0.165 ± 0.009

0.104

0.156 ± 0.008

0.191 ± 0.012

0.021

TA

0.077 ± 0.002

0.082 ± 0.005

NS

0.079 ± 0.004

0.091 ± 0.004

0.047

EDL

0.019 ± 0.001

0.019 ± 0.001

NS

0.021 ± 0.002

0.022 ± 0.002

NS

Soleus

0.018 ± 0.001

0.019 ± 0.002

NS

0.021 ± 0.001

0.020 ± 0.001

NS

Gastrocnemius

0.362 ± 0.008

0.387 ± 0.013

0.030

0.400 ± 0.010

0.407 ± 0.008

NS

Total

0.602 ± 0.006

0.718 ± 0.012

0.019

0.651 ± 0.015

0.710 ± 0.017

0.036

BAT

0.167 ± 0.017

0.378 ± 0.056

0.042

0.527 ± 0.028

0.796 ± 0.078

0.002

eWAT

1.199 ± 0.102

1.618 ± 0.186

0.042

1.882 ± 0.123

2.515 ± 0.098

0.001

rWAT

0.301 ± 0.035

0.536 ± 0.049

NS

0.749 ± 0.104

1.176 ± 0.096

0.005

sWAT

0.707 ± 0.075

0.777 ± 0.096

NS

1.578 ± 0.122

1.879 ± 0.108

0.041

mWAT

0.330 ± 0.051

0.314 ± 0.038

NS

0.939 ± 0.091

0.816 ± 0.238

NS

WAT total

1.940 ± 0.342

3.563 ± 0.348

0.079

5.035 ± 0.514

6.472 ± 0.354

0.017

  1. Abbreviations: wt, wild-type mice; Tg, transgenic mice; LFD, low-fat diet; HFD, high-fat diet; NS, non-significant.
  2. TA, tibialis anterior; EDL, extensor digitorum longus muscle; BAT, brown adipose tissue; eWAT, epididymal white adipose tissue; rWAT, retroperitoneal WAT; sWAT, subcutaneous WAT; mWAT, mesenteric WAT.
  3. The experimental data are presented as mean (g) ± SEM. 2-way ANOVA was used. n ≥ 11/group.
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