Figure 1: Mouse model of progressive chronic kidney disease: Plasma samples were collected at different time points in oxalate-rich diet fed mice as per the different stages of CKD. | Scientific Reports

Figure 1: Mouse model of progressive chronic kidney disease: Plasma samples were collected at different time points in oxalate-rich diet fed mice as per the different stages of CKD.

From: Circulating cathepsin-S levels correlate with GFR decline and sTNFR1 and sTNFR2 levels in mice and humans

Figure 1

We analyzed serum levels of Cat-S (A), sTNFR1 (B), and sTNFR2 (C) plotted with GFR at day 0, 1, 7, 14 and 21. D: Representative images of silver staining and F4/80 positive macrophages (source of Cat-S) in the kidneys of oxalate-rich diet fed mice at different time points. Data expressed as absolute individual values from 5–6 mice each group and Spearman correlation analysis was performed against change in GFR; level of significance for the correlations between GFR and Cat-S, sTNFR1 and sTNFR2 was p < 0.001, respectively.

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