Figure 6: Impact of ENM exposure on IgE meditated mast cell degranulation.
From: Contribution of engineered nanomaterials physicochemical properties to mast cell degranulation
BMMCs were exposed to ENMs (50 μg/ml) for 1 h followed by addition of DNP treatment (100 ng/ml) (black bars) and evaluated for the release of β-hexosaminidase into the supernatant. Values are expressed as mean ± SEM normalized to non-treated control group (n = 3/group). *Indicates significant difference between ENM-treated (white bars) and ENM + DNP-treated groups (black bars) (p ≤ 0.001). #Indicates significant difference between DNP-treated group (striped bar and dashed line) and ENM + DNP- treated groups (black bars) (p ≤ 0.05).
