Table 3 List of selected CVD affecting pathways regulated by both SBP and SBP’s plasma absorbed components.

1

AT1R_PATHWAY

Vasodilator and myocardial hypertrophy⁵⁵

2

SPPA_PATHWAY

Vasoconstriction and platelet activation

3

EPO_PATHWAY

Increasing erythrocyte⁵⁶

4

HIF_PATHWAY

Vascular remodeling and thrombopoietin⁵⁷

5

IL4_PATHWAY

Hematopoietic association⁵⁸

6

IL6_PATHWAY

Hematopoietic association⁵⁹

7

CARDIACEGF_PATHWAY

Cardiac hypertrophy and angiotensin⁶⁰

8

TPO_PATHWAY

Thrombopoietin⁶¹

9

ANGIOPOIETINRECEPTOR_PATHWAY

Angiopoietin⁶²

10

S1P_S1P1_PATHWAY

Endothelial cell induction⁶³

11

VEGFR1_PATHWAY

Vascular endothelial growth factor receptor⁶⁴

12

LYMPHANGIOGENESIS_PATHWAY

Angiogenesis⁶⁵

13

HEMATOPOIESIS_STAT3_TARGETS

Hematopoietic⁶⁶