Figure 4: Key bacterial alterations under low-dose penicillin treatment. | Scientific Reports

Figure 4: Key bacterial alterations under low-dose penicillin treatment.

From: Low-dose penicillin exposure in early life decreases Th17 and the susceptibility to DSS colitis in mice through gut microbiota modification

Figure 4

(a) Cladogram generated by LEfSe analysis showing enriched taxa in 2-week feces from control/metronidazol super-group (red) and penicillin group (green). (b) LDA scores of enriched taxa from a. (c) Heatmap showing relative abundance of key genera generated by LEfSe anaylsis. (d) Variance of segmented filamentous bacteria (SFB) relative abundance after penicillin treatment (1 μg/d · g bodyweight) quantified by qPCR. (e) SFB abundance changes under different levels of low-dose penicillin treatment. Data in d and e are expressed as relative fold difference to one of the samples and expressed as mean ± SEM. **P < 0.01, NS: not significant, one-way ANOVA.

Back to article page