Figure 5: Adipocyte cytokine secretion was altered by Aβ 1–40 stimulation.
From: Amyloid precursor protein modulates macrophage phenotype and diet-dependent weight gain
Adipocytes from wild type and APP−/− mice were isolated from subcutaneous adipose tissue and stimulated with or without 100 nM Aβ 1–40 overnight and media were collected to measure TNFα (a), IL-6 (b), IL-10 (c), IL-4 (d), IL-1β (e), MCP-1 (f), and adiponectin (g) secretion via ELISA. Data are expressed as mean +/− SD (n = 5),+,*p < 0.05.
