Figure 4: Verification of candidate proteins for KD diagnostic biomarkers by microarray ELISAs. | Scientific Reports

Figure 4: Verification of candidate proteins for KD diagnostic biomarkers by microarray ELISAs.

From: Identification of candidate diagnostic serum biomarkers for Kawasaki disease using proteomic analysis

Figure 4

Expression levels of the four candidate biomarkers were evaluated in the acute phase of KD and other infections that mimic KD, such as human adenovirus, Staphylococcus, and Streptococcus species. The serum concentrations of three proteins (LBP, LRG1, and RBP4) differed significantly in the acute phase of KD in comparison with these infections. The sera used in this experiment are described in Tables S1 and S3. The horizontal lines and error bars indicate means and SEMs, respectively. P values were used to evaluate the significance of differences between the acute phase of KD and these infections: ***p < 0.001; **p < 0.01; *p < 0.1; ns: non-significant.

Back to article page