Figure 3: DR inhibits proliferation and induces apoptosis in hepatocytes. | Scientific Reports

Figure 3: DR inhibits proliferation and induces apoptosis in hepatocytes.

From: Dietary restriction protects against diethylnitrosamine-induced hepatocellular tumorigenesis by restoring the disturbed gene expression profile

Figure 3

Representative images (a) and quantification (b) of proliferating hepatocytes by PCNA immunostaining of liver section, five 200× fields were counted for each liver section, and data were presented as the mean ± SEM (n = 3) (Scale bar, 50 μm), *P < 0.05. Representative images (c) and quantification (d) of cleaved-caspase3 immunostaining of liver sections, five 200× fields were counted for each liver section, and data were presented as the mean ± SEM (n = 3) (Scale bar, 20 μm), *P < 0.05. Representative immunoblot images (e) and quantification (f) of apoptosis-related proteins in liver lysates (n = 3), *P < 0.05, **P < 0.01.

Back to article page