Figure 3

Evidence of chromosome fission of (a) L. adleri HO174 chromosome 36 into 36.1 and 36.2; and (b) L. adleri SKINK-7 chromosome 30 into 30.1 and 30.2. Median read coverage (blue) and GC content (pink) were measured in 10 Kb blocks. Black horizontal lines indicate median coverage of that chromosome. The dashed line indicates the fission breakpoints on the original chromosomes: at 989,697 for chromosome 36 and 230,911 for chromosome 30. Genes transcribed from left to right (green) and from right to left (red) are homologous to L. major polycistronic transcriptional units from Thomas et al.67 with their transcription SSRs shown as arrows and origins of replication shown as black crosses.