Figure 1: Stimulation patterns used in this study.
From: Gene networks activated by specific patterns of action potentials in dorsal root ganglia neurons
(A) Shown are two patterns of electrical stimulation used throughout this study. For both 18/1 and 90/5 stimulation patters, an equal number of electrical pulses were delivered by bipolar stimulating electrodes across a Campenot chamber. 18/1 and 90/5 refer to 18 electrical stimuli delivered every minute (10 Hz) or 90 electrical stimuli (10 Hz) delivered once every 5 min for the duration of stimulation, respectively. In (B and C), is a representative image of a Campenot chamber used for long-term culture of DRG neurons showing axonal outgrowth (C) in the central compartment. Platinum electrodes deliver biphasic stimulation to both cell body compartments.
