Table 2 Enriched gene networks recruited by 90/5 action potential patterned stimulation for 5 hr.
From: Gene networks activated by specific patterns of action potentials in dorsal root ganglia neurons
Network | Score | Top Disease and Function | Focus Molecules |
|---|---|---|---|
1 | 39 | Cell Morphology, Connective Tissue Development and Function, Tissue Morphology | ABCC5, ABCF1, ATM/ATR, CDKAL1, CTU1, DDX52, DPH2, FAM120B, GPANK1, GULP1, HLCS, KIAA1161, MMS19, MON2, MSL2, MXD3, MYO18A, NCAPD3, NCAPH2, NKAP, ORAOV1, PHLPP1, PRIM2, RBM39, SLC12A2, SLC30A1, SLC38A2, SLC4A7, SLC7A1, SMC2, SMC3, SNX27, SRC |
2 | 38 | Neurological Disease, Small Molecule Biochemistry, Developmental Disorder | ACAD10, APP, ATCAY, CHCHD6, DPY19L3, FRMD8, GSPT2, HBS1L, IMP4, ISOC2, KCTD18, LETM2, LHFPL2, MAB21L2, NARF, ORMDL1, PATL1, PHACTR4, PLEKHO2, PUS7L, RAB39A, RCBTB1, RNF24, RP9, Rbfox3, SLC25A38, SLC41A3, TBC1D25, TCP11L2, UGGT2, ULK4, VAT1L, ZC2HC1A, ZNF322, ZNF35 |
3 | 37 | Post-Translational Modification, Cell Morphology, Cellular Assembly and Organization | AFAP1, ATE1, Ank2, CEP170, DUB, FTO, HERC2, KCNC4, KIF3A, KIF3B, KIF3C, MED20, NPR2, PAN2, PCYT1A, Par6, Pkc(s), RNF168, SLC18A3, SLC6A9, TRIM46, USP1, USP10, USP12, USP28, USP29, USP30, USP32, USP38, USP40, USP42, USP54, WDR20, WDR62, ZRANB1 |
4 | 37 | Cancer, Gastrointestinal Disease, Organismal Injury and Abnormalities | ABR, ADIPOR2, AGL, APPL1, CENPC, DARS2, DPYSL5, EIF5B, ERBB2IP, GAPVD1, INSM1, KCNA5, KCNS3, KCTD5, KIF26B, MINK1, MPP3, NELL1, NHLRC1, NIT1, NSL1, OCRL, PKNOX1, PRKAB2, RAB11FIP5, RPAP1, Rab11, Rab5, Rac, SLTM, TPCN2, TROVE2, ZBTB3, ZFYVE9, ZNF202 |
5 | 37 | Cell-To-Cell Signalling and Interaction, Cellular Movement, Cellular Development | Alpha catenin, BAG2, BSN, CCDC117, CDH2, CDH4, CDH8, CEP68, CTBP1, CTNND1, Cadherin, DEF6, ERC2, FOXJ3, HDAC11, IQSEC1, KCTD6, LTN1, MLF2, NUP85, OGT, PHF20, RBBP5, RBM22, RNF111, S1PR1, SATB1, SSPN, Spectrin, TJP1, TMEM117, TRIM26, TRMT2A, ZEB2, ZKSCAN8 |
