Figure 4

(a) Staining of cartilage cells with DAPI, TUNEL and MERGE. (b) Statistical graph and analysis of TUNEL staining, Pre-stimulated with the porous Se@SiO2 nanocomposites can significantly decrease apoptosis rates induced by H2O2. *P < 0.05. (c) Normalized by control group the cell activity decreased along with the increasing H2O2 concentrations. Significant protection of the porous Se@SiO2 nanocomposites as reflected by the cck-8 assay P < 0.05.