Figure 1 | Scientific Reports

Figure 1

From: Analysis of the common genetic component of large-vessel vasculitides through a meta-Immunochip strategy

Figure 1

Manhattan plot representation of the results of the HLA region in (A) giant cell arteritis, (B) Takayasu’s arteritis, and (C) the meta-analysis of both forms of vasculitis. The log10 of the P values are plotted against their physical chromosomal position. A red/green color gradient was used to represent the effect size of each analysed polymorphism (red for risk and green for protection). The red line represents the study-wide level of significance (P < 1.13E-06). HLA class I and II subregions are highlighted in grey.

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