Table 3 Genetic pleiotropy between giant cell arteritis and Takayasu’s arteritis using non-HLA data, HLA data only, and all Immunochip data.

From: Analysis of the common genetic component of large-vessel vasculitides through a meta-Immunochip strategy

Method

P-value

Non-HLA markers

HLA markers

All markers

REML

5.00E-03

5.00E-01

6.00E-03

PRS (GCA)

3.53E-03

2.68E-01

7.70E-02

PRS (TAK)

3.60E-02

6.97E-01

6.44E-01

  1. GCA, giant cell arteritis; HLA, human leukocyte antigen; PRS, polygenic risk score; REML, restricted maximum likelihood; TAK, Takayasu’s arteritis.
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