Table 3 Enriched histone modification detected with Enrichr (ENCODE Histone Modifications 2015) in the 46 selected genes.

From: Principal Components Analysis Based Unsupervised Feature Extraction Applied to Gene Expression Analysis of Blood from Dengue Haemorrhagic Fever Patients

Rank

Histone modification

P-value

adjusted P-values

Z-score

combines score

1

H3K4me1_fibroblast of dermis_hg19

1.60E-06

6.20E-04

−1.8

13.29

2

H3K4me1_bone marrow macrophage_mm9

4.90E-05

3.16E-03

−1.87

10.74

3

H3K4me1_myotube_hg19

4.90E-05

3.16E-03

−1.7

9.78

4

H3K4me1_K562_hg19

2.56E-05

3.16E-03

−1.66

9.54

5

H3K4me1_A549_hg19

3.03E-05

3.16E-03

−1.64

9.43

6

H3K4me1_skeletal muscle myoblast_hg19

4.90E-05

3.16E-03

−1.62

9.33

7

H3K4me2_K562_hg19

2.33E-04

1.00E-02

−1.74

8.03

8

H3K4me1_HepG2_hg19

2.33E-04

1.00E-02

−1.68

7.75

9

H3K4me1_HeLa-S3_hg19

2.33E-04

1.00E-02

−1.6

7.37

10

H3K4me1_fibroblast of lung_hg19

9.88E-04

2.94E-02

−1.73

6.12

11

H3K4me2_HeLa-S3_hg19

9.88E-04

2.94E-02

−1.71

6.02

12

H3K4me1_T-cell acute lymphoblastic leukaemia_hg19

9.88E-04

2.94E-02

−1.64

5.8

13

H3K27ac_osteoblast_hg19

9.88E-04

2.94E-02

−1.63

5.75

14

H3K4me3_Panc1_hg19

1.40E-03

3.61E-02

−1.59

5.27

15

H3K4me1_MEL cell line_mm9

1.39E-03

3.61E-02

−1.47

4.88

16

H3K27ac_A549_hg19

1.95E-03

4.71E-02

−1.53

4.68

17

H3K4me3_A549_hg19

2.14E-03

4.88E-02

−1.51

4.56

  1. Only those associated with adjusted P-values less than 0.05 are listed. Bold text indicates enrichment in the K562 cell line and is used in Fig. 1.