Figure 2: MCP-1 and sSiglec-9 activate M2-like macrophage differentiation in vitro.

(a) Phase contrast images of bone marrow macrophages (BMMs) cultured with DMEM, IL-4, MCP-1/sSiglec-9, alone or together with the CCR2 inhibitor, RS504393. Scale bar: 100 μm. (b) Relative mRNA expression levels in the treated BMMs (n = 4 per group). Data represent the mean ± SEM; ∗P < 0.05, ∗∗P < 0.01.