Figure 2: LocusZoom plots of –log10 p-values and r2 values of SNPs for the association, and rates of recombination in the regions analyzed according to 5 genes examined in the ADVANCE study. | Scientific Reports

Figure 2: LocusZoom plots of –log10 p-values and r2 values of SNPs for the association, and rates of recombination in the regions analyzed according to 5 genes examined in the ADVANCE study.

From: Evidence from single nucleotide polymorphism analyses of ADVANCE study demonstrates EFNB3 as a hypertension risk gene

Figure 2

The symbols (circles and diamonds) and the left-hand vertical axis illustrate –log10 p-values of the SNPs. Blue lines and the right-hand vertical axis represent rates of recombination in the chromosomal regions concerned. Red lines represent the Bonforroni-corrected p-value. The color of the symbols represents r2 values. The horizontal axis indicates the position in the chromosomes. The position of the EFNB3 gene is shown in the bottom of the figures.

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