Table 1 Numbers and percentages of hypertension cases and controls based on 140/90 mmHg or 160/100 mmHg cut-offs.

From: Evidence from single nucleotide polymorphism analyses of ADVANCE study demonstrates EFNB3 as a hypertension risk gene

Cases

number

% total

mean SBP (mmHg)

SD

mean DSP (mmHg)

SD

Males

140/90 mmHg cut-off

Actively treated

1264

70.5

149.5

20.7

82.9

10.7

>140/90 mmHg; not treated

530

29.5

156.0

14.6

85.2

9.3

Total

1794

     

160/100 mmHg cut-off

Actively treated so cannot be used

1264

87.2

149.5

20.7

82.9

10.7

>160/100 mmHg; not treated

185

12.8

171.7

12.0

90.2

8.9

Total

1449

     

Controls

140/90 mmHg cut-off

≤140/90 mmHg but ≥130/80 mmHg

425

81.7

126.6

9.2

74.8

7.3

130/80 mmHg cut-off

≤130/80 mmHg

95

18.3

119.2

7.7

70.3

5.9

Total

520

     

Females

140/90 mmHg cut-off

Actively treated

801

78.8

150.1

22.7

81.6

11.2

>140/90 mmHg; not treated

215

21.2

156.3

14.5

83.7

9.1

Total

1016

     

160/100 mmHg cut-off

Actively treated so cannot be used

801

92.4

150.1

22.7

81.6

11.2

>160/100 mmHg; not treated

66

7.6

176.4

16.4

90.5

11.0

Total

867

     

Controls

140/90 mmHg cut-off

<140/90 mHg but ≥130/80 mmHg

213

69.2

126.8

9.7

73.4

7.4

130/80 mmHg cut-off

<130/80

95

30.8

118.9

8.1

69.5

5.5

Total

308

     
  1. The numbers and percentages of cases and controls recruited into the study are provided based on whether they were actively treated, or based on BP measurements at the entry of the study. This information is calculated on 2 putative different BP cut-offs, i.e., 1) >140 or >90 mmHg for cases, and <140 and <90 mmHg for controls; 2) >160 or >100 mmHg for cases and <130 and <80 mmHg for controls. Means and SD of SBP (systolic blood pressure) and DBP (diastolic blood pressure) are also listed. For those cases actively treated for hypertension, since we do not have their real BP reading in the absence of medication, and they cannot be used in the in the high cut-off scenario, they are labels as “Actively treated so cannot be used” in the 160/100 mmHg cut-off group.