Table 4 Tests for independence of sexes with respect to allele frequencies for SNPs rs7141 and rs3744263.
Cases | Control | ||||||
|---|---|---|---|---|---|---|---|
Males | Females | χ2 test of independence (p-value) | Males | Females | χ2 test of independence (p-value) | ||
SNP rs7141 (imputed) | |||||||
A | N | 2562 | 1411 | 2.420 | 550 | 275 | |
Frequency | 0.714 | 0.694 | (0.120) | 0.647 | 0.645 | 0.003 | |
G | N | 1026 | 621 | 300 | 151 | (0.957) | |
Frequency | 0.286 | 0.306 | 0.353 | 0.355 | |||
SNP rs3744263 (genotyped) | |||||||
C | N | 2506 | 1378 | 2.502 | 535 | 268 | 0.0001 |
Frequency | 0.698 | 0.678 | (0.114) | 0.629 | 0.629 | (0.992) | |
T | N | 1082 | 654 | 315 | 158 | ||
Frequency | 0.302 | 0.322 | 0.371 | 0.371 | |||
