Table 1 Amount of lactoferrin absorbed by CaCO3 particles.

From: Formulation for Oral Delivery of Lactoferrin Based on Bovine Serum Albumin and Tannic Acid Multilayer Microcapsules

Approach

Weight of CaCO3 microparticles, mg

Amount of released Lactoferrin, mg

Lactoferrin absorbed, wt%

Co-precipitation (pH > 10)

60

0.3 ± 0.1a

0.5 ± 0.2

Co-precipitation (pH 8)

48

1.0 ± 0.1a

2.1 ± 0.2

Post-loading

60

0.7 ± 0.1b

1.2 ± 0.2

300

4.1 ± 1.5b

1.4 ± 0.5

600

7.6 ± 2.0b

1.3 ± 0.3

  1. Methods to measure Lf concentration: a-ELISA; b-HPLC.