Figure 6: CEOs downregulated mRNA expression of TLR4/MyD88 pathway and NLRP3 inflammasome. | Scientific Reports

Figure 6: CEOs downregulated mRNA expression of TLR4/MyD88 pathway and NLRP3 inflammasome.

From: The acute airway inflammation induced by PM2.5 exposure and the treatment of essential oils in Balb/c mice

Figure 6

mRNA levels were assayed by real-time RT-PCR using the ΔCt method. GAPDH was used as loading controls for mRNA expressions. CEOs downregulated mRNA expression of TLR4 (A), MyD88 (B), Nf-κB (C), NLRP3 (D) and P2 × 7 (E) of lung tissues. Data are expressed as mean ± standard error of the mean (**P < 0.01, *P < 0.05 versus the PM2.5 + saline group). CEOs reduced TLR4 (F) and NLRP3 (G) protein expression in lung tissues at all time-points, especially at bronchiole section.

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