Table 2 DFS of stage IV patients with CRCLM (Cohort I).

From: Correlations between TBL1XR1 and recurrence of colorectal cancer

Variables

Cases (n = 47)

3-year DFS (%)

DFS (months) Mean ± S.D.

P value

Gender

   

0.515

 Female

20

37.0%

31.2 ± 4.9

 

 Male

27

53.0%

35.5 ± 4.3

 

Age (year)

   

0.672

 <60

17

62.0%

37.1 ± 4.5

 

 ≥60

30

38.5%

32.1 ± 4.3

 

Primary tumor location

   

0.082

 Colon

34

48.5%

36.6 ± 3.9

 

 Rectum

13

41.0%

26.2 ± 4.8

 

Primary tumor differentiation

   

0.332

 Poor

15

59.3%

38.5 ± 5.8

 

 Well/Moderate

32

38.3%

30.9 ± 3.8

 

 CRCLM distribution

   

0.043*

 Unilobar

34

53.1%

37.6 ± 3.5

 

 Bilobar

13

25.4%

22.9 ± 6.3

 

No. of CRCLM

   

0.253

 <3

34

50.7%

36.2 ± 3.5

 

 ≥3

13

32.1%

28.0 ± 7.9

 

Resection Margin

   

0.031*

 R0

39

50.4%

36.1 ± 3.4

 

 R1

8

0.0%

15.3 ± 2.6

 

Adjunctive chemotherapy

   

0.007*

 Yes

37

52.7%

37.4 ± 3.6

 

 No

10

17.1%

19.3 ± 4.4

 

TBL1XR1 expression in CRC

   

0.014*

 Low

20

65.0%

43.7 ± 4.7

 

 High

27

30.9%

25.9 ± 3.6

 

TBL1XR1 expression in CRCLM

   

0.041*

 Low

13

49.5%

42.5 ± 7.0

 

 High

34

44.0%

30.1 ± 3.3

 
  1. Abbreviations: DFS, disease-free survival; TBL1XR1, Transducin (β)-like 1 X-linked receptor 1; CRC, colorectal cancer; CRCLM, colorectal cancer liver metastases.