Table 4 Expression of TBL1XR1 in TNM stage I-III CRC patients (Cohort II).

Variables	Cases (n = 146)	TBL1XR1 expression		χ² test P value
Variables	Cases (n = 146)	Low (n = 87)	High (n = 59)	χ² test P value
Gender				0.177
Female	50	26	24
Male	96	61	35
Age (year)				0.399
<60	73	46	27
≥60	73	41	32
Preoperative CEA level				0.664
<100 ng/ml	70	43	27
≥100 ng/ml	76	44	32
Tumor location				0.565
Colon	98	60	38
Rectum	48	27	21
Tumor size				0.020*
<5 cm	69	48	21
≥5 cm	77	39	38
Tumor differentiation				0.136
Poor	34	24	10
Well/Moderate	112	63	49
TNM stage				0.009*
I-II	88	60	28
III	58	27	31
Metachronous metastasis				0.046*
Absent	107	69	38
Present	39	18	21

Abbreviations: TBL1XR1, Transducin (β)-like 1 X-linked receptor 1; CRC, colorectal cancer; CRCLM, colorectal cancer liver metastases.

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