Table 5 DFS of the stage I-III CRC patients (Cohort II).

From: Correlations between TBL1XR1 and recurrence of colorectal cancer

Variables

Cases (n = 146)

5-year DFS (%)

DFS (months) Mean ± S.D.

Univariate P value

Multivariate P value

Gender

   

0.120

 

 Female

50

89.0%

105.3 ± 6.1

  

 Male

96

82.7%

91.6 ± 4.2

  

Age (year)

   

0.647

 

 <60

73

87.4%

98.6 ± 4.9

  

 ≥60

73

81.5%

94.5 ± 5.7

  

Preoperative CEA level

   

0.078

 

 <100 ng/ml

70

88.2%

101.6 ± 4.2

  

 ≥100 ng/ml

76

81.0%

90.8 ± 5.6

  

Tumor location

   

0.063

 

 Colon

98

86.6%

102.3 ± 4.4

  

 Rectum

48

80.6%

89.7 ± 5.0

  

Tumor size

   

<0.001*

0.001*

 <5 cm

69

90.4%

102.5 ± 5.2

  

 ≥5 cm

77

76.6%

85.0 ± 4.9

  

Tumor differentiation

   

0.591

 

 Poor

34

84.6%

98.0 ± 6.4

  

 Well/Moderate

112

84.3%

95.9 ± 4.6

  

TNM stage

   

0.174

 

 I-II

88

85.5%

99.7 ± 4.4

  

 III

58

83.1%

83.2 ± 5.0

  

Adjunctive chemotherapy

   

0.869

 

 No

100

82.0%

96.9 ± 4.4

  

 Yes

46

91.2%

87.8 ± 5.0

  

TBL1XR1 expression

   

<0.001*

<0.001*

 Low

87

93.2%

106.4 ± 4.1

  

 High

59

70.6%

77.1 ± 5.4

  
  1. Abbreviations: TBL1XR1, Transducin (β)-like 1 X-linked receptor 1; CRC, colorectal cancer.