Table 3 Meta-analysis of the association between high Ki-67 expression and clinicopathological features of RCC.

From: Prognostic and clinicopathological role of high Ki-67 expression in patients with renal cell carcinoma: a systematic review and meta-analysis

Variables

Studies

Pooled RR

95% CI

P Value

Model

Heterogeneity I2 (%)

P Value

TNM stage (III/IV vs. I/II)

4

2.03

1.68–2.44

<0.001

fixed

18.2

0.300

pT stage (T3/T4 vs. T1/T2)

8

1.67

1.35–2.06

<0.001

random

58.5

0.018

Metastasisa (yes vs. no)

5

2.15

1.77–2.62

<0.001

fixed

15.9

0.313

Fuhrman grade (III/IV vs. I/II)

8

1.77

1.20–2.60

0.004

random

95.2

<0.001

  1. aBoth lymph node and distant metastases; RR: relative ratio; CI: confidence interval; RCC: renal cell carcinoma.
Back to article page