Figure 6: C11orf83 plays an important role in inhibiting VSV replication in the absence of IFNs production.
From: Mitochondrial C11orf83 is a potent Antiviral Protein Independent of interferon production
(A) The absence of C11orf83 protein in Vero cells by Crispr-Cas9 system. (B–G) Effects of c11orf83 deletion to rVSV-GFP replication in Vero cells. (B) Representative imaging fluorescent shows the replication of rVSV-GFP in cells. (C) Quantitative RT-PCR results showing the relative change of N gene transcription. (D–F) Quantitative analysis of GFP positive cells and mean fluorescence intensity in cells by using flow cytometry. (G) Quantitative analysis of VSV-induced cells death using Trypan Blue staining.
