Figure 7: Cardiac nuclear morphology in an autopsied heart of a patient with EDMD.
From: Emerin plays a crucial role in nuclear invagination and in the nuclear calcium transient
(A) Confocal microscopic images of immunostaining for cTnT (red), emerin (green), and nuclei (blue) in control and EDMD-heart. The scale bar is 20 μm. (B) Bar graphs showing nuclear size in control and EDMD-heart (n = 65). The data are mean ± SD. (C) Bar graphs showing the percentages of cardiomyocytes with nuclear invagination in control and EDMD-heart (n = 65). The data are mean ± SE. *P < 0.05 compared to the control.
