Table 1 Demographics, clinical characteristics and cognitive function of participants.

From: Similarities and differences of functional connectivity in drug-naïve, first-episode adolescent and young adult with major depressive disorder and schizophrenia

Number (n)

MDD

SZ

HC

 

p

49

45

50

Demographic characteristic

Gender (male/female)

17/32

19/26

17/33

χ2 = 0.83

0.66

Age (years), mean ± SD

19.35 ± 6.03

18.42 ± 3.84

18.18 ± 3.92

F = 0.46

0.63

Education (years), mean ± SD

12.12 ± 3.77

10.71 ± 2.43

11.92 ± 2.60

F = 2.94

0.05

Clinical characteristic

HAMD score, mean ± SD

20.86 ± 8.70

9.52 ± 11.41

1.32 ± 1.65

F = 78.64

0.000

BPRS score, mean ± SD

23.08 ± 8.20

40.00 ± 13.03

18.26 ± 0.86

F = 38.39

0.000

HAMA score, mean ± SD

17.14 ± 8.81

6.93 ± 8.45

0.78 ± 2.16

F = 62.35

0.000

Duration of illness (months), mean ± SD

4.59 ± 6.28

4.32 ± 10.46

—

T = 0.158

0.88

Cognitive function

 

WCST

(n = 28)

(n = 29)

(n = 33)

  

correct responses

26.21 ± 10.78

19.52 ± 12.90

28.61 ± 12.80

F = 4.48

0.01

categories completed

2.89 ± 1.75

1.72 ± 1.89

3.70 ± 2.08

F = 8.17

0.001

Total errors

21.79 ± 10.78

28.55 ± 13.01

19.39 ± 12.80

F = 4.52

0.01

Perseverative errors

8.75 ± 7.27

14.10 ± 14.05

8.79 ± 9.54

F = 2.47

0.09

Non-perseverative errors

13.04 ± 5.19

14.38 ± 8.50

10.61 ± 5.12

F = 2.77

0.07

  1. MDD, Major depressive disorder; SZ, Schizophrenia; HC, Healthy controls; SD, Standard Deviation; HAMD, Hamilton Depression Rating Scale; BPRS, Brief Psychiatric Rating Scale; HAMA, Hamilton Anxiety Rating Scale, WCST, Wisconsin Card Sorting Test.
Back to article page