Figure 7: Structure-based sequence alignment of AtClpC1 NTD and AtClpD NTD with bacterial ClpC NTDs.

The sequences have been aligned using ClustalW. The residues forming helices are underlined and the helices are labelled α1 to α8 (ClpC numbering). The residues conserved among all seven sequences are highlighted in red, those conserved among five or six sequences are highlighted in green and those conserved in four sequences are highlighted in grey. The residues of regions that are substantially different in AtClpD structure have been given in blue. Mt, Cg, Cd, Bs and Bl corresponds to Mycobacterium tuberculosis, Corynebacterium glutamicum, Clostridium difficile, Bacillus subtilis and Bacillus lehensis, respectively.