Table 1 Effect of LTA₄H inhibitors to have entered the clinic and purportedly selective modulators on inhibition (IC₅₀) of the epoxide hydrolase (LTB₄ generation) and aminopeptidase (PGP degradation) activities of LTA₄H in our assays, as described in Materials and methods.

From: The development of novel LTA₄H modulators to selectively target LTB₄ generation