Figure 4: Overexpression of decorin activated the IGF1R-AKT-AP-1 pathway. | Scientific Reports

Figure 4: Overexpression of decorin activated the IGF1R-AKT-AP-1 pathway.

From: Overexpression of decorin promoted angiogenesis in diabetic cardiomyopathy via IGF1R-AKT-VEGF signaling

Figure 4

(A,B) The phosphorylation of AKT was decreased by HG treatment in a time-dependent manner. (C–E) The expression of IGF1R, Bcl2, and Bax and the phosphorylation of AKT. (F,G) The phosphorylation of AP-1. All data are presented as the mean ± SEM. *p < 0.05; **p < 0.01. #p < 0.05, compared to Con. &p < 0.05, &&p < 0.01, compared to HG + GFP.

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