Figure 4: Low levels of proinflammatory cytokines detected in the LPS-induced lung injury mice injected with iMSCs/BMMSCs.
From: Efficient Generation of Chemically Induced Mesenchymal Stem Cells from Human Dermal Fibroblasts
After 4 hours, LPS-treated mice were intratracheal instilled with PBS, fibroblasts, iMSCs, or BMMSCs. The expression levels of indicated proinflammatory cytokines in BALF were detected by Multiplex bead array assay. The levels of IL-1β, TNF-α, and TNF-β in BALF were quantified in three independent experiments. Data shows in means with ± SEM. *p < 0.05; **p < 0.01; n.s.: not significant.
