Table 2 Differentially expressed proteins between normal, degenerating and regenerating zebrafish retina as identified by 2D-DIGE.

From: Comparison of proteomic profiles in the zebrafish retina during experimental degeneration and regeneration

Spot No.

Accession

Peptide count

Protein Name

Fold change

R/D

D/N

R/N

954

B2GP30

17

Fructose-bisphosphate aldolase

2.18

0.51

1.11

604

F1Q8F1

10

Internexin neuronal intermediate filament protein

2.45

0.67

1.64

865

Q7ZUW8

10

Aspartate aminotransferase

2.65

0.29

0.71

866

Q6PC12

5

Enolase 1, (alpha)

2.12

0.34

0.72

1262

Q0D274

16

ES1 protein, mitochondrial

4.28

0.27

1.14

1083

E7F8G7

5

Plectin a

2.21

0.41

0.91

842

Q8AY63

28

Brain-subtype creatine kinase

3.12

0.43

1.35

879

Q6DH07

23

Arrestin 3, retinal (X-arrestin), like

2.20

0.46

1.00

703

Q6IQP5

36

Enolase 1, (Alpha)

2.18

0.48

1.03

876

F1R4Z2

8

Arrestin 3a, retinal (X-arrestin)

2.77

0.34

0.93

704

Q6IQP5

27

Enolase 1, (Alpha)

2.11

0.49

1.03

878

F1R4Z2

15

Arrestin 3a, retinal (X-arrestin

2.72

0.44

1.20

654

Q6NYE1

6

Fibrinogen, B beta polypeptide

0.23

2.95

0.68

1314

E7FES0

13

Apolipoprotein A-Ib

0.19

6.44

1.22

1291

E7FES0

10

Apolipoprotein A-Ib

0.33

2.01

0.66

904

Q6NYE1

9

Fibrinogen, B beta polypeptide

0.12

8.02

0.96

794

X1WCG6

7

Unknown

0.42

2.53

1.05

250

Q5RG12

3

Heat shock protein 90-alpha 2

0.18

4.39

0.80

  1. Protein spots were identified by mass spectrometry analysis.
  2. Proteins which show a 2-fold expression change were considered to be differentially expressed. Fold differences in expression between normal, degenerated and regenerating retina are shown in the table. (Numbers in Bold = 2-fold or more upregulated; Numbers in italics = 0.5-fold or less downregulated). N = normal retina; D = degenerated retina; R = regenerating retina.
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