Table 1 Interface area involved in the inter-subunit contacts of TTR WT, TTR A108V and TTR A108I.

From: Cavity filling mutations at the thyroxine-binding site dramatically increase transthyretin stability and prevent its aggregation

 

TTR WT

TTR A108V

TTR A108I

Dimer Interface Area (Å2)

1774

1731

1752

Tetramer Interface Area (Å2)

766

829

880

  1. TTR WT, A108V and TTR A108I are deposited under PDB codes 1F41, 5FW6 and 5FO2. The calculations were performed using PDBSum web server.
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