Figure 7: Toxic activity of BMAP-28 and its derivatives to cancer and healthy cells. | Scientific Reports

Figure 7: Toxic activity of BMAP-28 and its derivatives to cancer and healthy cells.

From: Mechanistic and structural basis of bioengineered bovine Cathelicidin-5 with optimized therapeutic activity

Figure 7

Peptide activity in (a) mouse B16-F1 melanoma cells, and (b) healthy bone marrow cells. (c) In vivo images of B16-F1 bearing mice (8 weeks male) injected via subcutaneous without (upper panel) and with (lower panel) 30 μM Syn1 peptide. (d) Measurement of the B16-F1 tumor volume in control and Syn1 treated group (n = 6). The tumor growth is shown inside the red circles. Data were presented as mean ± s.e.m.

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