Table 1 Lipid composition in different membrane systems.

From: Mechanistic and structural basis of bioengineered bovine Cathelicidin-5 with optimized therapeutic activity

In vitro (Large Unilamellar Vesicles)

Lipids

Thymocytes-like (mol %)47

Leukemia-like (mol %)47

E. coli like (mol %)46

Phosphatidylcholine

30.0

38.0

0.0

Phosphatidylethanolamine

11.0

22.0

80.0

Phosphatidylserine

0.0

7.0

0.0

Cholesterol

42.5

24.0

0.0

Sphingomyelin

10.0

0.0

0.0

Lyso-phosphatidylcholine

2.0

2.0

0.0

Lyso-phosphatidylethnolamine

1.5

2.0

0.0

Phosphatidylglycerol

0.0

0.0

15.0

Phosphatidylinsitol

3.0

5.0

0.0

Cardiolipin

0.0

0.0

5.0

In silico (Phospholipid-bilayer)

Phosphatidylcholine

30.0

38.0

0.0

Phosphatidylethanolamine

11.0

22.0

80.0

Phosphatidylserine

5.5

7.0

0.0

Cholesterol

42.5

24.0

0.0

Sphingomyelin

4.5

0.0

0.0

Lyso-phosphatidylcholine

2.0

2.0

0.0

Lyso-phosphatidylethnolamine

1.5

2.0

0.0

Phosphatidylglycerol

0.0

0.0

15.0

Phosphatidylinsitol

3.0

5.0

0.0

Cardiolipin

0.0

0.0

5.0

  1. The molar concentration shown in bold are different from the experimental lipid compositions. The percentage of anionic lipids in thymocytes-like membrane has been reciprocated with sphingomyelin.