Figure 4: Comparison of the transcriptional response to light of wild type and madC strains.

(A) Plot of gene transcript levels of the wild type vs madC strains by log₂FC. Red circles represent differentially expressed genes in response to light for the wild type, and blue dots those differentially expressed in the madC strain (FDR <0.05; log₂ fold-change ≥1). Grey dots represent genes that are not differentially expressed, and green dots are genes that do not pass the fold-change ≥|1| but have a significant change in the madC strain as determined by FDR. Diagonal lines (crossing the 0 of log₂FC for both strains) serve as a reference to identify genes in the borderline of the cut-off criteria. (B) Venn diagrams showing the overlap of the repressed and induced genes in response to light between the wild type and madC strains. (C) Category enrichment in differentially expressed genes (*FDR <0.2; **FDR <0.05). Color intensity represents the percentage of genes belonging to each category and includes GO terms for Biological Process and Molecular Function, which contain less than 900 and more than 5 genes. The dendrogram highlights clusters based on percentages of genes contained in each gene ontology.