Figure 5: Effects of PF on insulin resistance and insulin signaling pathway.

Serum fasting glucose (A), fasting insulin (B), HOMA-IR values (C), hepatic glycogen content (D) and western blotting results of IRS-1/Akt/GSK3β protein expression (E and F) after treatment with physiological saline (HFD) or paeoniflorin. Values are means ± SD. *P < 0.05 vs. Control group; #P < 0.05 vs. HFD group. n = 8 per group.