Figure 1: Catabolism of 1,2-PDL and propionate in S. Typhimurium.
From: Enzyme IIANtr Regulates Salmonella Invasion Via 1,2-Propanediol And Propionate Catabolism
1,2-PDL catabolism is achieved by the 1,2-PDL utilization operon, indicated in blue. 1,2-PDL is converted into propionyl-CoA within the polyhedral microcompartment. Propionate catabolism is accomplished by the propionate operon, indicated in purple. The common intermediate propionyl-CoA provides pyruvate through the 2-methylcitrate cycle (MCC), which can be used as an energy source. Oxygen or tetrathionate is used as an electron acceptor under aerobic or anaerobic conditions, respectively.
