Figure 1: Upregulated pathways in HD versus control blood. | Scientific Reports

Figure 1: Upregulated pathways in HD versus control blood.

From: Huntington’s disease blood and brain show a common gene expression pattern and share an immune signature with Alzheimer’s disease

Figure 1

Schematic representation of pathways collated from publicly available databases that are significantly upregulated in HD versus controls after correction for multiple testing (q < 0.05). Modules with similar gene content and functional annotation have been consolidated. Nodal shading is inversely proportional to false discovery rate threshold (q value); deep shades have low q values and pale shading is close to the 5% threshold. The weight of connecting lines is proportional to the number of genes shared between pathways.

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