Table 3 Univariate analysis for cancer-specific survival.
From: Tumor Wide Horizontal Invasion Predicts Local Recurrence for Scrotal Extramammary Paget’s Disease
Parameter | Patients(n) | Died of disease(n) | Pe | |
|---|---|---|---|---|
Age(years) | <70 | 184 | 11 | 0.530 |
≥70 | 22 | 1 | ||
Delay in diagnosis(years) | <7 years | 183 | 10 | 0.651 |
≥7 years | 23 | 2 | ||
Tumor size(cm2) | ≤25.0 | 120 | 8 | 0.482 |
>25.0 | 86 | 4 | ||
Multiple lesions | Absent | 183 | 12 | 0.169 |
Present | 23 | 0 | ||
Invasion level | In situ | 183 | 6 | <0.0001** |
Micro-invasion | 10 | 0 | ||
Deep invasion | 13 | 6 | ||
Nodule formation | Absent | 197 | 9 | <0.0001** |
Present | 9 | 3 | ||
Ulceration | Absent | 196 | 12 | 0.404 |
Present | 10 | 0 | ||
Lymphovascular invasion | Absent | 198 | 5 | <0.0001** |
Present | 8 | 7 | ||
Adnexa invasion | Absent | 178 | 8 | 0.017* |
Present | 28 | 4 | ||
Wide horizontal invasion | ≤2.0 cm | 154 | 10 | 0.584 |
>2.0 cm | 52 | 2 | ||
Recurrence disease | Absent | 183 | 10 | 0.651 |
Present | 23 | 2 | ||
Lymph node metastasis | Absent | 196 | 5 | <0.0001** |
Present | 10 | 7 | ||
Ki67 expression | <20% positive | 68 | 5 | 0.836 |
≥20% positive | 125 | 8 | ||
p53 expression | Negative | 72 | 9 | 0.026* |
Low expression | 115 | 1 | ||
High expression | 8 | 1 | ||
