Table 5 Multivariate Cox regression analysis for local recurrence-free survival.
From: Tumor Wide Horizontal Invasion Predicts Local Recurrence for Scrotal Extramammary Paget’s Disease
Variables | HR | 95%CI | Pf | |
|---|---|---|---|---|
Age | (<70 years/≥70 years) | 0.256 | 0.028–2.347 | 0.228 |
Delay in diagnosis | (<7 years/≥7 years) | 0.000 | 0.000–3.91E305 | 0.973 |
Recurrence disease | (Absent/Present) | 0.594 | 0.066–5.340 | 0.642 |
Tumor size | (≤25 cm2/>25 cm2) | 0.514 | 0.137–1.938 | 0.326 |
Multiple lesions | (Absent/Present) | 0.924 | 0.219–3.903 | 0.914 |
Nodule formation | (Absent/Present) | 0.000 | — | 0.986 |
Lymphovascular invasion | (Absent/Present) | 0.001 | — | 0.997 |
Adnexa invasion | (Absent/Present) | 0.000 | 0.000–8.91E289 | 0.971 |
Wide horizontal invasion | (≤2.0 cm/>2.0 cm) | 5.142 | 1.262–20.956 | 0.022* |
Invasion level | — | — | 0.999 | |
In situ | 1 | — | — | |
Micro-invasion | 0.000 | — | 0.976 | |
Deep invasion | 0.000 | — | 0.983 | |
Lymph node metastasis | (Absent/Present) | 2.347 | — | 1.000 |
p53 expression | — | — | 0.418 | |
Negative | 1 | — | — | |
Low expression | 4.248 | 0.496–36.370 | 0.187 | |
High expression | 0.000 | — | 0.982 | |
Ki67 expression | (<20%/≥20% positive) | 1.566 | 0.369–6.648 | 0.543 |
