Table 2 Microarray validation by PCR-Array.

From: Genomic reprograming analysis of the Mesothelial to Mesenchymal Transition identifies biomarkers in peritoneal dialysis patients

GENE

Non-Epithelioid

Fold change

p-value

FDR

GREM1

7.82

<0.001

 

IL1B

27.70

<0.001

<0.001

KRT34

37.36

<0.001

<0.001

CDH13

65.76

<0.001

<0.001

THBS1

25.87

<0.001

<0.001

COL6A3

43.34

<0.001

<0.001

MMP1

16.81

<0.001

<0.001

COL13A1

7.71

<0.001

<0.001

IL6

2.52

0.015

0.017

FSP1

11.32

<0.001

<0.001

TFPI2

26.61

<0.001

<0.001

CAV1

4.51

<0.001

<0.001

VCAN

4.94

<0.001

<0.001

IL33

8.08

<0.001

<0.001

ITGA11

7.26

<0.001

<0.001

THBS2

3.93

<0.001

<0.001

MMP3

10.50

<0.001

<0.001

SNAI1

3.65

<0.001

<0.001

COL1A2

2.12

0.021

0.024

CD44

8.41

<0.001

<0.001

MMP2

4.28

<0.001

<0.001

FAP

3.04

<0.001

<0.001

CTSK

2.94

<0.001

<0.001

CLDN1

0.32

<0.001

<0.001

COL4A6

0.43

<0.001

<0.001

WT1

0.36

<0.001

<0.001

HSPB8

0.48

<0.001

<0.001

ITGB4

0.38

<0.001

<0.001

AQP1

0.19

<0.001

<0.001

VTN

0.20

<0.001

<0.001

BMP4

0.21

<0.001

<0.001

CDH3

0.28

<0.001

<0.001

HSPA2

0.42

<0.001

<0.001

KDR

0.21

<0.001

<0.001

CDH1

0.08

<0.001

<0.001

LAMA5

0.24

<0.001

<0.001

CXCL14

0.19

<0.001

<0.001

BMP7

0.07

<0.001

<0.001

THBD

0.05

<0.001

<0.001

PRG4

0.06

<0.001

<0.001

  1. A total of 40 genes, 22 induced and 18 repressed, were selected from Non-Epithelioid group in microarray and validated by RT-qPCR. Fold change, p-value (One-sample Limma test) and associated FDR multiple testing correction are show. Normal letter: up-regulated genes; bold: down-regulated genes in microarrays.
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