Figure 5: Hierarchical clustering analysis of individual intact mass profiles.

Heatmap based on abundances of each central MUP mass, calculated as a proportion of the total intact mass urinary MUP profile for each individual urine sample (n = 137). The data set (protein: rows, individual animals: columns) was subjected to hierarchical clustering using the GMD package (ver 0.3.3, function heatmap 3) in R. Euclidean distances were calculated and median method applied for clustering and generating trees for both proteins and samples.