Table 1 Sample characteristics.

From: Dissociable diffusion MRI patterns of white matter microstructure and connectivity in Alzheimer’s disease spectrum

 

SCI (n = 30)

MCI (n = 55)

AD (N = 79)

Group differences

Age

63.0 ± 9.5

65.5 ± 11.2

70.2 ± 8.1

*(AD > MCI; AD > SCI)

Gender, % females

53

36

58

*(AD♀ > MCI♀)

MMSE § , score

29.4 ± 0.6

28.0 ± 2.2

22.3 ± 5.4

*(AD < MCI; AD < SCI)

Education §§ , years

15.0 ± 3.9

14.0 ± 3.2

12.2 ± 3.2

*(AD < MCI; AD < SCI)

Heal coil, % 8HRBRAIN

67

69

62

No significant group effect

APOE status N (% ε4+ † )

23 (17)

41 (44)

54 (76)

*(ADε4+ > MCIε4+ > SCIε4+)

  1. §MMSE missing for 5 MCI, and 2 SCI.
  2. §§Years of education not available for 1 SCI, 4 MCI, 7 AD.
  3. †% ε4+ denotes the percentage of participants with known APOE status who had at least one ε4 allele.
  4. *Significant main effect of group (P < 0.05) based on univariate linear models. “>” and “<” denote significant group differences (P < 0.05) in the indicated direction based on post-hoc testing using Bonferroni-correction for three comparisons.
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