Scientific Reports

Table 3 Comparison of the folding kinetics of UCH-L1, -L3 and -L5_N240.

From: Entropic stabilization of a deubiquitinase provides conformational plasticity and slow unfolding kinetics beneficial for functioning on the proteasome

	UCH-L1	UCH-L3	UCH-L5_N240
(s⁻¹)	0.3 ± 0.1	49 ± 20	0.14 ± 0.03
m_f (kcal mol⁻¹ M⁻¹)	−1.06 ± 0.10	−1.28 ± 0.10	−1.09 ± 0.07
(s⁻¹)	(7.6 ± 2.3)e-5	(2.6 ± 0.9)e-4	(8.1 ± 7.6)e-9
m_u (kcal mol⁻¹ M⁻¹)	0.74 ± 0.04	0.83 ± 0.03	1.88 ± 0.12
m_kin (kcal mol⁻¹ M⁻¹)	1.80 ± 0.11	2.11 ± 0.10	2.97 ± 0.14
ΔG (kcal mol⁻¹)	4.90 ± 0.27	7.19 ± 0.32	9.86 ± 0.57
[D]_50% (M)	2.72 ± 0.13	3.41 ± 0.13	3.33 ± 0.15

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