Figure 6: EGb761 inhibits SAPK and JAK-STAT signalings in the kidneys of brain death rats.

(A) The expression and phosphorylation status of JNK-MAPK, p-38-MAPK, and STAT3 in renal tissue were assessed by Western blot. Representative immunoblots of the indicated proteins were shown. (B) Protein levels were quantified and normalized to GAPDH. Data was presented as mean ± SD. *P < 0.05, *2P < 0.01, *3P < 0.001; significantly different from the sham group. aP < 0.05, a2P < 0.01 vs. BD; significantly different from the BD group. bP < 0.05, b2P < 0.01,b3P < 0.001; significantly different from the BD + EGb b48h group. n = 5 per group.