Figure 4: Overexpression of PPARβ/δ by Ad-PPARβ/δ Prevented Cerebral VSMC Switch to Synthetic Phenotype. | Scientific Reports

Figure 4: Overexpression of PPARβ/δ by Ad-PPARβ/δ Prevented Cerebral VSMC Switch to Synthetic Phenotype.

From: PPARβ/δ, a Novel Regulator for Vascular Smooth Muscle Cells Phenotypic Modulation and Vascular Remodeling after Subarachnoid Hemorrhage in Rats

Figure 4

(A) Representative image and quantitative analysis of PPARβ/δ at 48 hours after transfection with Ad-PPARβ/δ or Ad-GFP in cerebral VSMC (n = 3 per group). (B) Representative image and quantitative analysis of PPARβ/δ, α-SMA, SM-MHC, Smemb and OPN expression in cerebral VSMC at 24 hours after Hb incubation with or without Ad-PPARβ/δ pretreated respectively (n = 3 per group). All data were presented as mean ± standard deviation. *P < 0.05 vs. Control, ##P < 0.05 vs. Ad-PPARβ/δ; #P < 0.05 vs. Hb + Ad-PPARβ/δ.

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