Figure 6: Effect of hnRNP A2/B1 on the HIV-1 LTR promoter in cells. | Scientific Reports

Figure 6: Effect of hnRNP A2/B1 on the HIV-1 LTR promoter in cells.

From: The cellular protein hnRNP A2/B1 enhances HIV-1 transcription by unfolding LTR promoter G-quadruplexes

Figure 6

(a) hnRNP A2/B1 depletion in 293T cells by siRNAs analysed by western blot with anti hnRNP A2/B1 antibody. Scra indicates scrambled siRNAs. Detection of α-tubulin (αt) was used as control. The symbol“/”indicates untreated cells. (b) Analysis of the luciferase activity of the wt and M4 + 5 LTR promoters in 293T cells treated with hnRNP A2/B1 siRNAs, normalized to protein content.

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