Figure 3: Fractional anisotropy (FA)-weighted white matter network connectivity among the areas that were affected by the addiction × rs1137070 interaction.
From: MAOA rs1137070 and heroin addiction interactively alter gray matter volume of the salience network
(A) The ACC-OFC.R, ACC-TPO.R, ACC-INS.R, ACC-OFC (TPO).L, OFC (TPO).L-TPO.R, and OFC (TPO).L-OFC.R connections significantly increased in heroin abusers (shown in red), and the INS.R-TPO.R connection significantly decreased in heroin abusers (shown in blue). The ACC had the most significant connections with the other regions. (B) T values of each connection in this network. OFC (TPO).L, left orbital frontal cortex and temporal pole; OFC.R, right orbital frontal cortex; TPO.R, right temporal pole; INS.R, right insula; ACC, bilateral anterior cingulate cortex. The p value for each connection is presented in Table S3.
